If it were my tank, I'd go ahead and treat. There are enough signs of bloat to do so, IMO.
There is no way to be 100% sure, unless you can find a vet willing to treat fish, but with the losses you have had and the symptoms involved, I would want to do something rather than wait it out and lose more fish.
There are two treatments below my signature for bloat.
I would do a large water change and substrate vacuuming before initiating any treatment.
I agree with Robin on your water change amounts, as well.
Kim
There is no way to be 100% sure, unless you can find a vet willing to treat fish, but with the losses you have had and the symptoms involved, I would want to do something rather than wait it out and lose more fish.
There are two treatments below my signature for bloat.
I would do a large water change and substrate vacuuming before initiating any treatment.
I agree with Robin on your water change amounts, as well.
Kim