Well, this is a good idea.I read 1 post on here a few months back, and the guy stated that the bone had some effect on his water?It was a bear skull, he said,it was only in the tank like 2 days or something, and it killed his fish.
But I reckon sunbleaching the deer skull, and setting it out where ants/beetles and other insects, or crawlers could clean it off, and then just rinse it in water, and maybe scrub with a soft/fine brush could do it.
But even doing the above, and covering the skull in epoxy or clear coating with somethin'would be alright.Just not something that'd give the skull a 'shiny look.