Well, as far as leaking issues are concerned, I haven't had any problems with my in-line and its connected to an EHEIM. And the heaters come with 3/4 inch and 1/2 inch connections which fit most pipes, and if not there are reducers/expander adapters that can tackle the diameter issue.
As far as ajustment or emergency work is concerned, I don't know exactly your setup with the stand and where the canister's will be situated, but with me, i placed the heater inside my cabinet with the EHEIM and other stuff hidden from sight but easily accessible.
The Rena Smart Heater is well reviewed, and realistically, that will probably work for you just as well. With good placement and using 2 good heaters (preferably submersible), it should be fine. The review section here is good, you just need to read ALL of the reviews to get the whole context of the performance of these products (some people don't know the meaning of an "objective" review). You may benefit from 2 thermometers as well.
Hope that helps..
Out of pure curiosity, what floor of your flat/house will you be placing this beauty of a tank?